设计了一种基于荧光成像的X射线光束在线监测装置,用于上海光源硬X射线光束的实时在线监测。相较于现有位置监测器和气体电离室,该装置能实现2 kHz高速采集,具有实时监测光束位置、通量、尺寸以及重建入射光波前相对变化量的功能,且不会影响下游实验开展。该装置可用于光学器件和实验位置反馈,在超长和微纳聚焦光束线站将有很好的应用。在上海光源时间分辨超小角散射线站的USAXS和微聚焦SAXS实验站利用该装置开展在线监测实验,采集并分析了常用实验帧率下的光束稳定性数据,得到了该线站光束位置、通量、尺寸分布的时频域信号和入射波前的相对变化情况,验证了该装置的可行性。

Traditionally, optical microscopy is used to visualize the morphological features of pathogenic bacteria, of which the features are further used for the detection and identification of the bacteria. However, due to the resolution limitation of conventional optical microscopy as well as the lack of standard pattern library for bacteria identification, the effectiveness of this optical microscopybased method is limited. Here, we reported a pilot study on a combined use of Structured Illumination Microscopy (SIM) with machine learning for rapid bacteria identification. After applying machine learning to the SIM image datasets from three model bacteria (including Escherichia coli, Mycobacterium smegmatis, and Pseudomonas aeruginosa), we obtained a classification accuracy of up to 98%. This study points out a promising possibility for rapid bacterial identification by morphological features.

以艾灸前后血流灌注指数为观察对象,研究艾灸对人体微循环的作用。将10个人分别进行不同时间(10 min、15 min、20 min)的艾灸和物理加热,使用激光散斑血流仪对检测区域进行测量和成像,观察各组穴区血流灌注指数的变化。经艾灸或者物理加热后,穴位处的血流灌注指数均有明显升高并有一个峰值,艾灸峰值出现在停止加热后,物理加热峰值出现在加热时间内,停止加热后,艾灸效应持续时间比物理加热长。研究表明,艾灸能够引起穴位局部微循环血流量增加,并与其作用于机体的时间有关,艾灸对机体产生作用的最主要原因是温热效应。